The EPSG provides active support for implementing openSAFETY on top of any and all data transfer protocols, and also offers help e.g. for certification and conformance tests. The open source license of this TÜV-certified protocol stack ensures that the technology is a very secured investment for all users.
The data transfer protocol that carries safety frame traffic has no bearing at all on the functionality of the safety protocol. This is called the Black Channel principle: all safety-oriented mechanisms are exclusively implemented on the application level, which enables total independence from the underlying transport layer. A brief look at the basic structure of data transfer protocols may serve to illustrate the principle.